Sildalist

Description

Last updated on: October 9, 2024

What Is Sildalist and How Does it Work?

It is a medication that combines two active ingredients: sildenafil citrate and tadalafil. It is used to treat erectile dysfunction (ED) in men.

Sildalist is a phosphodiesterase type 5 (PDE5) inhibitor, which means it works by increasing blood flow to the penis during sexual stimulation.

How Does Sildalist Work?

• Relaxing the muscles: It relaxes the muscles in the penis, allowing for increased blood flow.
• Increasing blood flow: Sildalist increases blood flow to the penis, which helps to achieve and maintain an erection.
• Blocking PDE5: It blocks the action of PDE5, an enzyme that breaks down cGMP, a chemical that helps to relax the muscles and increase blood flow.

Uses

Sildalist is used to treat:

• Erectile dysfunction: It is used to treat erectile dysfunction, a condition characterized by the inability to achieve or maintain an erection.
• Pulmonary arterial hypertension: It is used to treat pulmonary arterial hypertension, a condition characterized by high blood pressure in the lungs.

Side Effects

• Headache: It can cause headaches, which can range from mild to severe.
• Flushing: It can cause flushing, which can lead to a feeling of warmth or redness in the face, neck, and chest.
• Nausea and vomiting: It can cause nausea and vomiting, especially when first starting the medication.
• Dizziness and lightheadedness: It can cause dizziness and lightheadedness, which can increase the risk of falls.

Interactions

• Nitrates: It should not be taken with nitrates, as this can increase the risk of a sudden and severe decrease in blood pressure.
• Alpha-blockers: Sildalist should not be taken with alpha-blockers, as this can increase the risk of a sudden and severe decrease in blood pressure.
• Riociguat: It should not be taken with riociguat, as this can increase the risk of a sudden and severe decrease in blood pressure.

Dosage

The dosage of Sildalist varies depending on the condition being treated. The typical dosage is:

• 50mg per day: The typical starting dosage of Sildalist is 50 mg per day, taken orally.
• 100mg per day: The dosage of Sildalist can be increased to 100 mg per day, taken orally, if necessary.

Precautions with Sildalist

• Pregnant women: Sildalist should be used with caution in pregnant women, as it can increase the risk of birth defects.
• Breastfeeding women: It should be used with caution in breastfeeding women, as it can pass into breast milk and cause side effects in the baby.
• Children and adolescents: It should be used with caution in children and adolescents, as it can increase the risk of suicidal thoughts and behaviors.